Moradyn® Purple corn
  Moradyn® is an active plant ingredient characterized by a specific phytocomplex that contribute to normalize the blood sugar levels.(I) Color of extract is an intense dark purple, due to the high content of anthocyanins.
   
 

CHARACTERISTICS

check Unique standardized extract obtained from the fruit of proprietary purple variety of mais (Zea Mays L.) entirely cultivated in Italy
check Synergic action of bioactive compounds
check Mechanism of action identified “in vitro”
check Dark purple powder for use in nutritional supplements
check Compliant with main worldwide markets food regulations
check Suggested dosage:  500 mg a day

PurpleCorn

Digestive System

 

HEALTH BENEFITS OF MORADYN®

 

Moradyn® bioactive compounds contribute to the blood sugar levels normalization through enzymatic activity on α-glucosidase, one of the key enzyme involved, in the intestinal lumen, to the carbohydrate digestion and absorption. (II)

These compounds are also positively capable to prevent the major risk factors related to metabolic syndrome, like obesity, insulin resistance, dysmetabolism and hypertension thaks to the inhibition of the formation of the Advanced Glycation end-products (AGEs) which are physiologically accumulated by aging (III,IV).

SCIENTIFIC EVIDENCE

In vitro antiglycative activity was evaluated by incubated glucose in absence/presence of extract at different concentration for 28 days.(VI)

These results have been obtained using aminoguanidine as control reference and show Moradyn® extract inhibitory capacity at all tested concentrations.

In vitro hypoglycemic activity was evaluated by incubating the α-glucosidase enzyme in presence of extract at different concentrations.(VII)

These results have been obtained using acarbose as control reference and demonstrated Moradyn® extract capacity to inhibit α-glucosidase enzyme.

 

SPECIFICATIONS

check 0,2% (HPLC w/w) of α-glucosidase inhibiting activity (Chemical)
check 10% (UV-vis) of phenols with anti-glycative compound
check 3% (UV-vis) of α-glucosidase inhibiting activity (Enzymatic)

 

 

Cyanidin 3 O glucoside

References

  1. Escudero F. et al. Purple corn (Zea mays L.) phenolic compounds profile and its assessment as an agent against oxidative stress in isolated mouse organs. J. Med Food (2012), 15 (2): 206–215
  2. Lao F. et al. Quantification of Purple Corn (Zea mays L.) Anthocyanins Using Spectrophotometric and HPLC Approaches: Method Comparison and Correlation. Food Anal. Methods 9:1367–1380 (2016)
  3. Nowotny K.et al. Advanced glycation end products and oxidative stress in type 2 diabetes mellitus.Biomolecules, 5, 194 (2015).
  4. Baynes J.W. The role of AGEs in aging: causation or correlation. Exp. Gerontol., 36, 1527 (2001).
  5. Ferron L. et al. A New Italian Purple Corn Variety (Moradyn) Byproduct Extract: Antiglycative and Hypoglycemic In Vitro Activities and Preliminary Bioaccessibility Studies. Molecules.2020 Apr 23;25(8):1958-1979
  6. Maietta M. et al. Artichoke (Cynara cardunculus L. var. scolymus) waste as a natural source of carbonyl trapping and antiglycative agents. Food Research International (Ottawa, Ont.), 03 Aug 2017, 100(Pt 1):780-790
  7. Chen C. et al. Chemical characterization of proanthocyanidins in purple, blue, and red maize coproducts from di erent milling processes and their antiinflammatory properties. Ind. Crops Prod. 2017, 109, 464–475

 

 

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