Moradyn® is the dried extract of Maiz morado, the purple-blue color botanical variety of Zea Mays L. native of Perù. The corn fruit constitutes a rich source of anthocyanins, pigments known for their several beneficial properties: anti-oxidant, anti-inflammatory, cardioprotective and neuroprotective.
C-3-G (cyanidin-3-O-β-D-glucoside), the predominant anthocyanin among the others, performs an action on the physiological mechanisms related to obesity and to type 2 diabetes (1-3).
Fig.1: Molecular structure of Cyanidin 3-glucoside
In vivo studies show the effectiveness of purple corn anthocyanins in normalizing serum insulin, glucose and lipid and body weight when associated with a high fat diet (3)
C-3-G, specifically, increases gene- expression of adiponectin in adipose tissue and improves vasodilation endothelium-dependent and inhibit atherogenesis (2,3).
In vivo experiments have shown the short and long-term anti-hyperglycemic activity of anthocyanins that help to maintain constant serum glucose levels (1).
Fig.2: C-3-G stimulate adiponectin expression in human adipocytes.
Moradyn® dry extract of purple corn fruits is standardized in polyphenols and anthocyanins, both present as glycosides and in acylated form:
NLT 10,0% Polyphenols (Folin- Ciocalteu)
NLT 5% Anthocyanins (UV / Eu.Ph)
Moradyn® dry extract complies to the specifications according to Belfrit project directives.
Moradyn® can be used as food supplement or in association with other active ingredients with a suggested daily dosage of 500 mg (1).
1.Hong S, Heo J, Kim J, Kwon S, Yeo K et al. (2013) Antidiabetic and Beta Cell-Protection Activities of Purple Corn Anthocyanins. Biomol Ther 21(4):284-289.
2. Liu Y, Li D, Zhang Y et al (2014). Anthocyanin increases adiponectin secretion and protects against diabetes-related endothelial dysfunction. Physiol Endocrinol Metab 306, E975-E988.
3. Tsuda T, Horio F, Uchida K et al (2003).Dietary Cyanidin 3-O-β-DGlucoside- Rich Purple Corn Color Prevents Obesity and Ameliorates Hyperglycemia. Mice J Nutr 133(7):2125-2130.
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All statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.