Moradyn®

Moradyn® is the dried extract of Maiz morado, the purple-blue color botanical variety of Zea Mays L. native of Perù. The corn fruit constitutes a rich source of anthocyanins, pigments known for their several beneficial properties: anti-oxidant, anti-inflammatory, cardioprotective and neuroprotective.

C-3-G (cyanidin-3-O-β-D-glucoside), the predominant anthocyanin among the others, performs an action on the physiological mechanisms related to obesity and to type 2 diabetes (1-3).

Fig.1: Molecular structure of Cyanidin 3-glucoside

Anti-obesity action
In vivo studies show the effectiveness of purple corn anthocyanins in normalizing serum insulin, glucose and lipid and body weight when associated with a high fat diet (3)
C-3-G, specifically, increases gene- expression of adiponectin in adipose tissue and improves vasodilation endothelium-dependent and inhibit atherogenesis (2,3).

Antidiabetic action
In vivo experiments have shown the short and long-term anti-hyperglycemic activity of anthocyanins that help to maintain constant serum glucose levels (1).

Fig.2: C-3-G stimulate adiponectin expression in human adipocytes.

Specifications 
Moradyn® dry extract of purple corn fruits is standardized in polyphenols and anthocyanins, both present as glycosides and in acylated form:
NLT 10,0% Polyphenols (Folin- Ciocalteu)
NLT 5% Anthocyanins (UV / Eu.Ph)

Moradyn® dry extract complies to the specifications according to Belfrit project directives.

Dosage 
Moradyn® can be used as food supplement or in association with other active ingredients with a suggested daily dosage of 500 mg (1).

Bibliography 
1.Hong S, Heo J, Kim J, Kwon S, Yeo K et al. (2013) Antidiabetic and Beta Cell-Protection Activities of Purple Corn Anthocyanins. Biomol Ther 21(4):284-289.
2. Liu Y, Li D, Zhang Y et al (2014). Anthocyanin increases adiponectin secretion and protects against diabetes-related endothelial dysfunction. Physiol Endocrinol Metab 306, E975-E988.
3. Tsuda T, Horio F, Uchida K et al (2003).Dietary Cyanidin 3-O-β-DGlucoside- Rich Purple Corn Color Prevents Obesity and Ameliorates Hyperglycemia. Mice J Nutr 133(7):2125-2130.

Disclaimer: this article is for information only and should not be used for the diagnosis or treatment of medical conditions. All reasonable care have been used by FLANAT in compiling the information but make no warranty as to its accuracy. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions.
All statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

 

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Disclaimer

All scientific data contained in this web site are for information only and should not be used for the diagnosis or treatment of medical conditions. All reasonable care have been used by FLANAT in compiling the information but make no warranty as to its accuracy. Please verify with your National Health Agency before using any of the listed ingredients.